C. Ivas

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GLYCEMIA AND LIPIDEMIA VARIATIONS OF THE RABBITS INOCULATED WITH BEE VENOM

C. Ivas, Gh. Solcan, Geta Pavel, Ionela Burcă, Mariana Pavel

Abstract
Besides the toxic, inflammatory and allergic effect of the bee venom on the mammals the researches in the last decades made also evident its therapeutic effects. To prevent the dismetabolic disease and their consequences on the human being and animals a great attention is paied to the study on the controlling mechanisms of glycemia and lipidemia. In this connection, the present study made evident the serum level variations of glucose, cholesterol and triglycerides 2, 6 and 24 h after the inoculation of the bee venom to rabbits by applying 3 stings (E1 group), 6 stings ( E2 group) and 12 stings (E3 group). The obtained results are indicative of a reducing tendency of glycemia 2 h after inoculation at the E1 group while with the E2 and E3 groups the serum glucose level showed a gradual increase without exceeding the physiological reference limits along the whole experiment (due to both the secretion stimulation of catecholamines and the corticosteroidic effect). The levels of cholesterol and serum triglycerides showed a significant gradual decrease with every experimental group 2 and 6 h after inoculation and the recovery of the initial values after 24 h for E1 and E2 but maintained at lower values than the average of the reference at E3.

Key words: bee venom, sting, rabbit, serum glucose, serum cholesterol, serum triglycerides